Publications

TREHALOSE, AN ALTERNATIVE TO DMSO TO CRYOPRESERVE HUMAN PLURIPOTENT STEM CELLS.

Aikaterini Ntai, Simona Baronchelli, Alberto La Spada, Pasquale De Blasio, Ida Biunno. Submitted.

EPIGENETIC AND TRANSCRIPTIONAL MODULATION OF WDR5, A CHROMATIN REMODELING PROTEIN, IN HUNTINGTON’S DISEASE HUMAN INDUCED PLURIPOTENT STEM CELL (HIPSC) MODEL.

Simona Baronchelli, Alberto La Spada, Aikaterini Ntai, Paola Conforti, Serena Redaelli, Angela Bentivegna, Pasquale De Blasio, Ida Biunno. Mol Cell Neurosci. 2017 May 2;82:46-57. doi: 10.1016/j.mcn.2017.04.013

A REVIEW OF RESEARCH GRADE HIPSCS QUALIFICATION AND BIOBANKING PROCESSES.

Aikaterini Ntai, Simona Baronchelli, Alberto La Spada, Anna Moles, Alessandro Guffanti, Pasquale De Blasio, Ida Biunno. Biopreserv Biobank. 2017 Apr 7. doi: 10.1089/bio.2016.0097

CELL LINE MACROARRAY: AN ALTERNATIVE HIGH-THROUGHPUT PLATFORM TO ANALYZE HIPSC LINES.

Alberto La Spada, Simona Baronchelli, Linda Ottoboni, Francesca Ruffini, Gianvito Martino, Nunzia Convertino, Aikaterini Ntai, Tobias Steiner, Ida Biunno, Andrea De Blasio. J Histochem Cytochem. 2016 Dec;64(12):739-751. doi: 10.1369/0022155416673969

DNA METHYLATION PROFILES OF HUMAN PLURIPOTENT STEM CELLS, A VfERSATILE TOOL TO INVESTIGATE CELL IDENTITY AND BIOSAFETY.

Simona Baronchelli and Ida BiunnoInsight in Stem Cells. 2016,2,1:13. doi: article/2016/pdf.

EPIGENETIC TARGETING OF GLIOMA STEM CELLS: SHORT-TERM AND LONG-TERM TREATMENTS WITH VALPROIC ACID MODULATE DNA METHYLATION AND DIFFERENTIATION BEHAVIOR, BUT NOT TEMOZOLOMIDE SENSITIVITY.

Gabriele Riva, Valentina Butta, Chiara Cilibrasi, Simona Baronchelli, Serena Redaelli, Leda Dalprà, Marialuisa Lavitrano, Angela Bentivegna.Oncol Rep. 2016;35(5):2811-24. doi: 10.3892/or.2016.4665

INVESTIGATING DNA METHYLATION DYNAMICS AND SAFETY OF HUMAN EMBRYONIC STEM CELL DIFFERENTIATION TOWARDS STRIATAL NEURONS

Simona Baronchelli, Alberto La Spada, Paola Conforti, Serena Redaelli, Leda Dalprà, Pasquale De Blasio, Elena Cattaneo, Ida Biunno. Stem Cells Dev. 2015;24(20):2366-77. doi: 26132372

EVALUATION OF CROSS-SAMPLE CONTAMINATION IN TISSUE MICROARRAYS BY POLYMERASE CHAIN REACTION

D’Urso Davide G., La Spada Alberto, Tramonte Tommaso, Rainoldi Barnaba, and De Blasio Andrea. Biopreservation and Biobanking. June 2015, 13(3): 219-223. doi: 10.1089/bio.2014.0040.

TISSUE MICROARRAY TECHNOLOGY FOR MOLECULAR APPLICATIONS: INVESTIGATION OF CROSS-CONTAMINATION BETWEEN TISSUE SAMPLES OBTAINED FROM THE SAME PUNCHING DEVICE

Erik Vassella, José A. Galván and Inti Zlobec. Microarrays 2015, 4, 188-195; doi:10.3390/microarrays4020188.

SEL1L SNP RS12435998, A PREDICTOR OF GLIOBLASTOMA SURVIVAL AND RESPONSE TO RADIO-CHEMOTHERAPY

Marta Mellai, Monica Cattaneo, Alessandra Maria Storaci, Laura Annovazzi, Paola Cassoni, Antonio Melcarne, Pasquale De Blasio, Davide Schiffer, Ida Biunno. Oncotarget, 2015 Apr 10, 5. doi:oncotarget/article/2015.

ADDITIONAL CONGENERS OF THE MACROLIDE NEAUMYCIN: STRUCTURE REVISION AND BIOLOGICAL ACTIVITY

Matteo Simone, Sonia I Maffioli, Arianna Tocchetti, Stefano Tretter, Monica Cattaneo, Ida Biunno, Eleonora Gaspari and Stefano Donadio.
J Antibiot (Tokyo). 2015 Jan 14. doi: 10.1038/ja.2014.168.

IN VITRO ANTICANCER DRUG TEST: A NEW METHOD EMERGES FROM THE MODEL OF GLIOMA STEM CELLS

Gabriele Riva, Simona Baronchelli, Laura Paoletta, Valentina Butta, Ida Biunno, Marialuisa Lavitrano, Leda Dalprà, Angela Bentivegna. Toxicology Reports. 2014;188–199. doi:10.1016/j.toxrep.2014.05.005

OVERVIEW ON TECHNIQUES TO CONSTRUCT TISSUE ARRAYS WITH SPECIAL EMPHASIS ON TISSUE MICROARRAYS

Ulrich Vogel. Microarrays 2014, 3(2), 103-136. doi: 10.3390/microarrays3020103.

FIBROBLASTS MAINTAINED IN 3 DIMENSIONS SHOW A BETTER DIFFERENTIATION STATE AND HIGHER SENSITIVITY TO ESTROGENS

Claudia Montani, Nathalie Steimberg, Jennifer Boniotti, Giorgio Biasiotto, Isabella Zanella, Giuseppe Diafera, Ida Biunno, Luigi Caimi, Giovanna Mazzoleni, Diego Di Lorenzo.
Toxicol Appl Pharmacol. 2014 Nov 1;280(3):421-33. doi: 10.1016/j.taap.2014.08.021.

A MIRNA SIGNATURE IN HUMAN CORD BLOOD STEM AND PROGENITOR CELLS AS POTENTIAL BIOMARKER OF SPECIFIC ACUTE MYELOID LEUKEMIA SUBTYPES

Cattaneo M, Pelosi E, Castelli G, Cerio AM, D’Angiò A, Porretti L, Rebulla P, Pavesi L, Russo G, Giordano A, Turri J, Cicconi L, Lo-Coco F, Testa U, Biunno I.
J Cell Physiol. 2014 Dec 11. doi: 10.1002/jcp.24876.

BIOBANKING SHIFTS TO “PRECISION MEDICINE”

Ntai A, Baronchelli S, Pellegrino T, De Blasio P, Biunno I
Journal of Biorepository Science for Applied Medicine. 2014;2014:2, 11-15. doi: 10.2147/BSAM.S46559

APPLICATION OF TISSUE MICROARRAY TECHNOLOGY TO STEM CELL RESEARCH

La Spada A., Rainoldi B., De Blasio A. and Biunno I.
Microarrays 2014, 3(3), 159-167; doi:10.3390/microarrays3030159

BRCA1 POINT MUTATIONS IN PREMENOPAUSAL BREAST CANCER PATIENTS FROM CENTRAL SUDAN

Ida Biunno, Gitana Aceto, Khalid Dafaallah Awadelkarim, Annalisa Morgano, Ahmed Elhaj, Elgaylani Abdalla Eltayeb, Dafalla Omer Abuidris, Nasr Eldin Elwali, Chiara Spinelli, Pasquale De Blasio, Ermanna Rovida, Renato Mariani-Costantini
Familial Cancer (2014); 13:437 – 444. doi: 10.1007/s10689-014-9717-4

TISSUE MICROARRAY (TMA) VERSUS WHOLE SECTION IMMUNOHISTOCHEMISTRY IN THE ASSESSMENT OF ER/PR AND HER-2/NEU STATUS IN A BREAST CANCER SERIES FROM SUDAN

Awadelkarim KD, Arizzi C, Elamin EO, Osman I, Mekki SO, Biunno I, Barberis MC, Mariani-Costantini R.
Breast J. 2013 Jul-Aug;19(4):446-7. doi: 10.1111/tbj.12144.

EUROPEAN, MIDDLE EASTERN, AND AFRICAN SOCIETY FOR BIOPRESERVATION AND BIOBANKING (ESBB). 2012 CONFERENCE SESSION ON BIOBANKING IN EMERGING COUNTRIES

Rita T. Lawlor, Patrick M. Sluss, Rupert Langer, Maher A. Sughayer, Michael A. Igbe, Khalid Siddiqui, Pasquale De Blasio, Bonginkosi Duma, Maimuna Mendy, Christian Chabannon, and Muntaser Ibrahim. Biopreserv Biobank. 2013 Jun;11(3):176-81. doi: 10.1089/bio.2013.0017.

CELL AND TISSUE MICRO ARRAY TECHNOLOGIES FOR PROTEIN AND NUCLEIC ACID EXPRESSION PROFILING

M. Cardano, G. Diaferia, M. Falavigna, C. Spinelli, F. Sessa, P. De Blasio, I.Biunno.
J Histochem Cytochem. Feb 2013; 61(2): 116–124. doi:  10.1369/0022155412470455

EXPRESSION ANALYSIS OF SPARC/OSTEONECTIN IN ORAL SQUAMOUS CELL CARCINOMA PATIENTS: FROM SALIVA TO SURGICAL SPECIMEN

Aquino G, Sabatino R, Cantile M, Aversa C, Ionna F, Botti G, La Mantia E, Collina F, Malzone G, Pannone G, Losito NS, Franco R, Longo F.
Biomed Res Int. 2013;2013:736438. doi: 10.1155/2013/736438

CYTOSOLIC PHOSPHORYLATED EGFR IS PREDICTIVE OF RECURRENCE IN EARLY STAGE PENILE CANCER PATIENTS: A RETROPECTIVE STUDY

Di Lorenzo G, Perdonà S, Buonerba C, Sonpavde G, Gigantino V, Pannone G, Quarto G, Ferro M, Gaudioso G, Terracciano D, Di Trolio R, Rescigno P, Botti G, De Placido S, Facchini G, Ascierto PA, Franco R.
J Transl Med. 2013; 11(1):161. doi:10.1186/1479-5876-11-161.

DELINEATING THE CYTOGENOMIC AND EPIGENOMIC LANDSCAPES OF GLIOMA STEM CELL LINES

Baronchelli S, Bentivegna A, Redaelli S, Riva G, Butta V, Paoletta L, Isimbaldi G, Miozzo M, Tabano S, Daga A, Marubbi D, Cattaneo M, Biunno I, Dalprà L.
PLoS One. 2013;8(2):e57462. doi: 10.1371/journal.pone.0057462

TISSUE MICROARRAY DESIGN AND CONSTRUCTION FOR SCIENTIFIC, INDUSTRIAL AND DIAGNOSTIC USE

Pilla Daniela,Bosisio M. Francesca, Roberto Marotta, Faggi Stefano, Forlani Paolo, Falavigna Maurizio, Biunno Ida, Martella Emanuele, De Blasio Pasquale, Borghesi Simone, Cattoretti Giorgio.
J Pathol Inform. 2012;3:42. doi: 10.4103/2153-3539.104904.

PEGFR-TYR 845 EXPRESSION AS PROGNOSTIC FACTORS IN ORAL SQUAMOUS CELL CARCINOMA

Aquino G, Pannone G, Santoro A, Liguori G, Franco R, Serpico R, Florio G, de Rosa A, Mattoni M, Cozza V, Botti G, Losito S, Longo F, Staibano S, Cuda G, Lo Muzio L, Sbordone C, Bufo P, Grimaldi A, Caraglia M, Di Domenico M.
Cancer Biol Ther. 2012 Sep;13(11):967-77. doi: 10.4161/cbt.20991.

THE FIRST REPORTED GENERATION OF SEVERAL INDUCED PLURIPOTENT STEM CELL LINES FROM HOMOZYGOUS AND HETEROZYGOUS HUNTINGTON’S DISEASE PATIENTS DEMONSTRATES MUTATION RELATED ENHANCED LYSOSOMAL ACTIVITY

Camnasio S, Carri AD, Lombardo A, Grad I, Mariotti C, Castucci A, Rozell B, Riso PL, Castiglioni V, Zuccato C, Rochon C, Takashima Y, Diaferia G, Biunno I, Gellera C, Jaconi M, Smith A, Hovatta O, Naldini L, Di Donato S, Feki A, Cattaneo E.
Neurobiol Dis. 2012 Apr;46(1):41-51. doi: 10.1016/j.nbd.2011.12.042

MOLECULAR CHAPERONES AS THERAPEUTIC TARGETS TO COUNTERACT PROTEOSTASIS DEFECTS

Cattaneo M, Dominici R, Cardano M, Diaferia G, Rovida E,Biunno I.
J Cell Physiol. 2012 Mar;227(3):1226-34. doi: 10.1002/jcp.22856

SEL1L, AN UPR RESPONSE PROTEIN, A POTENTIAL MARKER OF COLONIC CELL TRANSFORMATION

Ashktorab H, Green W, Finzi G, Sessa F, Nouraie M, Lee EL, Morgano A, Moschetta A, Cattaneo M, Mariani-Costantini R, Brim H,Biunno I.
Dig Dis Sci. 2012 Apr;57(4):905-12. doi: 10.1007/s10620-011-2026-y

MESENCHYMAL STROMAL CELL CRYOPRESERVATION

Sabrina Renzi, Tina Lombardo, Silvia Dotti, Sara Dessì, Pasquale De Blasio and Maura Ferrari.
Biopreserv Biobank. June 2012, 10(3): 276-281. doi:10.1089/bio.2012.0005

SUB-SAHARAN CENTRALIZED BIOREPOSITORY FOR GENETIC AND GENOMIC RESEARCH

N. Gasmelseed, AA Elsir, P.De Blasio and I. Biunno
Sci Total Environ. 2012 Apr 15;423:210-3. doi: 10.1016/j.scitotenv.2010.07.054

THE SCIENCE OF STEM CELL BIOBANKING:INVESTING IN THE FUTURE

Diaferia GR., Cardano M., Cattaneo M., Dessì SS., Spinelli C., De Blasio P., Biunno I
J Cell Physiol. 2012 Jan;227(1):14-9. doi: 10.1002/jcp.22732

COMPREHENSIVE OUTSOURCING BIOBANKING FACILITY TO SERVE THE INTERNATIONAL RESEARCH COMMUNITY

Diaferia GR., Biunno I., DeBlasio P
Biopreserv Biobank. 2011 Jun;9(2):191-4. doi: 10.1089/bio.2011.0002

MSEL-1L (SUPPRESSOR/ENHANCER LIN12-LIKE) PROTEIN LEVELS INFLUENCE MURINE NEURAL STEM CELL SELF-RENEWAL AND LINEAGE COMMITMENT

Cardano M, Diaferia GR, Cattaneo M, Dessì SS, Long Q, Conti L, DeBlasio P, Cattaneo E, Biunno I
J Biol Chem. 2011 May 27;286(21):18708-19. doi: 10.1074/jbc.M110.210740

SYSTEMATIC CHROMOSOMAL ANALYSIS OF CULTURED MOUSE NEURAL STEM CELL LINES

Diaferia G., Conti L., Redaelli S., Cattaneo M., DeBlasio P., Dalpra L., Cattaneo E., Biunno I
Stem Cells Dev. 2011 Aug;20(8):1411-23. doi: 10.1089/scd.2010.0359

CELLULE STAMINALI DAL DERMA DI INDIVIDUI ADULTI

Diaferia G., Cardano M., DeBlasio P., Biunno I.
Hi.tech dermo 3:2729 (2009)

MARBLE ARCH INTERNATIONAL WORKING GROUP ON BIOBANKING FOR BIOMEDICAL RESEARCH

Riegman PH., Morente MM., Betsou F., De Blasio P., Geary P.
Mol. Oncol 2:213-222 (2008)

PATHOLOGICAL, CLINICAL AND PROGNOSTIC CHARACTERISTICS OF BREAST CANCER IN CENTRAL SUDAN VERSUS NORTHERN ITALY: IMPLICATIONS FOR BREAST CANCER IN AFRICA

Awadelkarim KD., Arizzi C., Elamin EOM., Hamad HMA,  De Blasio P., Mekki SO., Biunno I., Elwali NE., Costantini RM.,  Barberis M.
Histopathology. 2008 Mar;52(4):445-56. doi: 10.1111/j.1365-2559.2008.02966.x

IS STEM CELL CHROMOSOMAL STABILITY AFFECTED BY CRYOPRESERVATION CONDITIONS?

Diaferia G., Dessì S., DeBlasio P., Biunno I.
Cytotechnology. Sep 2008; 58(1): 11–16. doi:  10.1007/s10616-008-9163-y

THE TISSUE BANKING IN CANCER AND STEM CELL RESEARCH

Graziano A., Biunno I., DeBlasio P., Giordano A.
J Cell Physiol. 2007 Aug;212(2):345-7. doi: 10.1002/jcp.21098

TISSUE MIROARRAYS – A CROSS OVER VALIDATION TOOL IN PATHOLOGY

Maffe M., Falavigna M., Barberis M., Arizzi C., Awadelkarim KD., Biunno I., Kononen J., deBlasio P.
Cell Preservation Technology 5(1):44 (2007)

A SIMPLE EXTRACTION METHOD USEFUL TO PURIFY DNA FROM DIFFICULT BIOLOGICAL SOURCES

Oliveri C.,Frequin M., Malferrari G., Saltini G., Gramegna M., Tagliabue R, DeBlasio P., Biunno I., Biagiotti L.
Cell Preservation Technology. 2006, 4(1): 51-54. doi: 10.1089/cpt.2006.4.51

AUTOMATED SYSTEMS FOR NUCLEIC ACIDS EXTRACTION, PURIFICATION AND ANALYSIS

Malferrari G., Monferini E., Saltini G., Michelini S., Proverbio MC., Biagiotti L., Gervasi F., De Blasio P., Biunno I.
BIOforum 5:2-4 (2004)

HIGH-QUALITY PROTOZOAN AND HEPATITIS B VIRUS (HBV) DNA FROM DIFFERENT BIOLOGICAL SPECIMENS

Biagiotti L., Gramegna M., Valisi M., Madama S., Saltini G., Dominici R., Malferrari G., Monferini E., Proverbio M., De Blasio P., Biunno I.
Laboratory Medicine 35(11):1-3 (2004)

HIGH QUALITY GENOMIC DNA FROM HUMAN WHOLE BLOOD AND MONONUCLEAR CELLS

Malferrari G., Monferini E., DeBlasio P., Diaferia G., Del Vecchio E., Bernardi LR., Biunno I.
Biotechnique 33: (6) 1228-1230 (2002)