Workflow & Traceability

A modern TMA workflow must maintain a reliable link between donor tissue, sampled region, TMA spot, digital slide and analysis result.

Visiopharm interface video

Use this video near the traceability explanation to show how Galileo TMA connects donor tissue, array position and downstream digital analysis.

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End-to-end TMA traceability

Traceability is not only a software feature. It is the backbone of reliable TMA construction and digital pathology analysis.

1

Donor ID

Record donor block or sample identifiers.

2

ROI selection

Associate tissue regions with selected coordinates.

3

Core transfer

Document the transfer from donor position to recipient position.

4

TMA map

Create a recipient block map for sectioning and scanning.

5

Analysis link

Support de-arraying and scoring in digital pathology tools.

Illustrated workflow overview

Below are two complementary visual summaries of the Galileo TMA workflow, from tissue and slide selection to TMA construction, slide preparation and AI-supported core analysis, plus downstream applications.

Workflow diagram showing selection of tissues, slides and areas of interest, digital scanning, TMA construction with Galileo TMAtic, TMA slide preparation, XML export and TMA core analysis with Visiopharm. — End-to-end Galileo TMA workflow: tissue selection, digital scanning, ROI selection, TMA construction, slide preparation, XML traceability and downstream digital pathology analysis.

Workflow and applications figure showing FFPE blocks and slides, AI-based analysis, Galileo TMAtic, organoids, spatial omics, visual mass spectroscopy, quantitative imaging and DNA RNA workflows. — Tissue Microarray Core Facility workflow and applications: Galileo TMAtic integrated with AI-based slide analysis, organoids and spheroids, spatial omics, multiplex imaging and DNA/RNA extraction workflows.

Applications-oriented workflow

Galileo TMA is presented as an enabling platform for research and diagnostic-development applications. The workflow connects tissue selection, precise core transfer, TMA slide preparation, digital scanning and downstream analysis.

Biomarker validation on large tissue cohorts
Spatial omics and multiplexed imaging
Digital pathology and AI-supported core analysis
Organoid, spheroid and frozen tissue array research
DNA/RNA extraction and molecular profiling from selected cores

From sample to application

The same TMA block can support multiple analytical paths: immunohistochemistry, multiplex staining, spatial biology, quantitative image analysis and molecular workflows. This makes Galileo TMA useful as a core-facility platform for standardized, reproducible sample preparation.

Traceability features to highlight

ID

Sample identity

Maintain donor block, tissue core and recipient spot identity throughout the process.

XML

Export-ready data

Make TMA maps and coordinate information usable in downstream software workflows.

AI

Image-analysis ready

Prepare the TMA for digital pathology scoring, segmentation and multiplex analysis.